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Details on Person Diagram of Potential therapeutics for SARS
| Class:Id | PathwayDiagram:9679574 |
|---|---|
| _displayName | Diagram of Potential therapeutics for SARS |
| _timestamp | 2021-08-24 01:48:37 |
| created | [InstanceEdit:9679575] Gillespie, Marc E, 2020-03-24 |
| height | 1052 |
| modified | [InstanceEdit:9687978] Jassal, Bijay, 2020-05-13 [InstanceEdit:9689575] Matthews, Lisa, 2020-05-20 [InstanceEdit:9689702] Jassal, Bijay, 2020-05-21 [InstanceEdit:9689798] Matthews, Lisa, 2020-05-21 [InstanceEdit:9690219] Matthews, Lisa, 2020-05-27 [InstanceEdit:9690310] Jassal, Bijay, 2020-05-29 [InstanceEdit:9690426] Jassal, Bijay, 2020-06-01 [InstanceEdit:9690466] Jassal, Bijay, 2020-06-01 [InstanceEdit:9690485] Wu, G, 2020-06-01 [InstanceEdit:9690502] Jassal, Bijay, 2020-06-02 [InstanceEdit:9690511] Jassal, Bijay, 2020-06-02 [InstanceEdit:9690546] Jassal, Bijay, 2020-06-02 [InstanceEdit:9690955] Jassal, Bijay, 2020-06-08 [InstanceEdit:9691190] Jassal, Bijay, 2020-06-09 [InstanceEdit:9691213] Jassal, Bijay, 2020-06-09 [InstanceEdit:9691226] Jassal, Bijay, 2020-06-10 [InstanceEdit:9691244] Jassal, Bijay, 2020-06-10 [InstanceEdit:9691245] Jassal, Bijay, 2020-06-10 [InstanceEdit:9691249] Jassal, Bijay, 2020-06-10 [InstanceEdit:9691250] Jassal, Bijay, 2020-06-10 [InstanceEdit:9691333] Jassal, Bijay, 2020-06-11 [InstanceEdit:9693552] Jassal, Bijay, 2020-07-02 [InstanceEdit:9693820] Jassal, Bijay, 2020-07-07 [InstanceEdit:9696616] Jassal, Bijay, 2020-07-23 [InstanceEdit:9699066] Matthews, Lisa, 2020-09-09 [InstanceEdit:9715064] Stephan, Ralf, 2021-02-16 [InstanceEdit:9731761] Stephan, Ralf, 2021-05-24 [InstanceEdit:9732444] Stephan, Ralf, 2021-05-27 [InstanceEdit:9733527] Stephan, Ralf, 2021-06-07 [InstanceEdit:9734386] Stephan, Ralf, 2021-06-17 [InstanceEdit:9751248] Matthews, Lisa, 2021-08-24 |
| representedPathway | [Pathway:9679191] Potential therapeutics for SARS [Homo sapiens] |
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reactionType="Association"> <Inputs> <Input id="354" points="432 984" /> <Input id="355" points="446 934" /> </Inputs> <Outputs> <Output id="356" /> </Outputs> <Properties> <displayName>ITGA4:ITGB1 binds natalizumab</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="372" reactomeId="9679421" points="717 948, 718 948, 745 933" position="718 948" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="373" points="676 968" /> <Input id="374" points="674 927" /> </Inputs> <Outputs> <Output id="375" /> </Outputs> <Properties> <displayName>PDCD1 binds PDCD1 inhibitors</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="381" reactomeId="9679839" points="952 950, 951 948, 1014 927" position="951 948" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="383" points="917 930" /> <Input id="1572" points="930 981" /> </Inputs> <Outputs> <Output id="384" /> </Outputs> <Properties> <displayName>RIPK1 binds ponatinib</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="399" reactomeId="9678854" points="1205 961, 1208 960, 1248 936" position="1208 960" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="400" points="1165 929" /> <Input id="401" points="1165 977" /> </Inputs> <Outputs> <Output id="402" /> </Outputs> <Properties> <displayName>S1PR1 binds S1PR1 agonists</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="447" reactomeId="9679477" points="1471 986, 1472 985, 1522 985" position="1472 985" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="448" points="1431 1014" /> <Input id="1505" points="1424 970" /> </Inputs> <Outputs> <Output id="450" /> </Outputs> <Properties> <displayName>VEGFA-165 dimer binds VEGFA inhibitors</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="898" reactomeId="9681169" points="506 400, 506 400, 550 400" position="506 400" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="899" points="473 422" /> <Input id="900" points="477 379" /> </Inputs> <Outputs> <Output id="901" /> </Outputs> <Properties> <displayName>CRBN binds IMiDs</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="922" reactomeId="9679044" points="337 527, 339 529, 390 529" position="339 529" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="924" points="284 527" /> <Input id="1418" points="297 501" /> </Inputs> <Outputs> <Output id="925" /> </Outputs> <Properties> <displayName>FKBP1A binds sirolimus</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1151" reactomeId="9678749" points="690 773, 690 773, 749 773" position="690 773" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1152" points="672 806" /> <Input id="1153" points="656 745" /> </Inputs> <Outputs> <Output id="1154" /> </Outputs> <Properties> <displayName>IMPDH tetramers binds IMPDH inhibitors</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1307" reactomeId="9678561" points="1698 839, 1700 838, 1777 896" position="1700 838" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1301" points="1794 811" /> <Input id="1552" points="1650 897" /> </Inputs> <Outputs> <Output id="1311" /> </Outputs> <Properties> <displayName>IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1312" reactomeId="9679028" points="2017 550, 2018 550, 2052 572" position="2018 550" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1313" points="2060 523" /> <Input id="1314" points="1997 550" /> </Inputs> <Outputs> <Output id="1317" /> </Outputs> <Properties> <displayName>JAK3 binds JAK3 inhibitors</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1353" reactomeId="9680836" points="1643 408, 1644 409, 1684 409" position="1644 409" lineWidth="1.0" isForDisease="true" lineColor="255 0 0" reactionType="Association"> <Inputs> <Input id="1354" points="1617 392" /> <Input id="1355" points="1615 431" /> </Inputs> <Outputs> <Output id="1356" /> </Outputs> <Properties> <displayName>NS5B binds ribavirin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1366" reactomeId="9680443" points="1285 650, 1286 650, 1325 650" position="1286 650" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1367" points="1254 683" /> <Input id="1368" points="1252 644" /> </Inputs> <Outputs> <Output id="1369" /> </Outputs> <Properties> <displayName>ROCK1,2 bind ROCKi</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1374" reactomeId="9679816" points="1269 430, 1269 429, 1308 426" position="1269 429" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1375" points="1213 466" /> <Input id="1376" points="1229 395" /> </Inputs> <Outputs> <Output id="1377" /> </Outputs> <Properties> <displayName>SIGMAR1 binds dextromethorphan</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1378" reactomeId="9679780" points="1299 520, 1301 520, 1331 520" position="1301 520" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1379" points="1260 535" /> <Input id="1375" points="1227 496" /> </Inputs> <Outputs> <Output id="1380" /> </Outputs> <Properties> <displayName>SIGMAR1 binds fluvoxamine</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1381" reactomeId="9679819" points="1669 544, 1668 544, 1713 544" position="1668 544" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1383" points="1631 554" /> <Input id="1478" points="1627 534" /> </Inputs> <Outputs> <Output id="1384" /> </Outputs> <Properties> <displayName>TBK1 binds amlexanox</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1400" reactomeId="9685830" points="1501 295, 1501 295, 1549 295" position="1501 295" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1401" points="1471 284" /> <Input id="1402" points="1471 311" /> </Inputs> <Outputs> <Output id="1403" /> </Outputs> <Properties> <displayName>TUBB binds colchicine</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1454" reactomeId="9678925" points="1226 229, 1225 228, 1269 228" position="1225 228" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1455" points="1211 215" /> <Input id="1456" points="1206 261" /> </Inputs> <Outputs> <Output id="1457" /> </Outputs> <Properties> <displayName>NR3C1 binds NR3C1 agonists</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1475" reactomeId="9690461" points="328 590, 328 591, 388 591" position="328 591" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1476" points="294 590" /> <Input id="924" points="267 542" /> </Inputs> <Outputs> <Output id="1477" /> </Outputs> <Properties> <displayName>FKBP1A binds tacrolimus</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1495" reactomeId="9679029" points="1803 192, 1803 193, 1849 193" position="1803 193" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1496" points="1772 171" /> <Input id="1497" points="1709 228" /> </Inputs> <Outputs> <Output id="1498" /> </Outputs> <Properties> <displayName>C-ter TLR7 dimer binds HCQ</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1502" reactomeId="9679045" points="1804 266, 1804 265, 1852 266" position="1804 265" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1503" points="1765 314" /> <Input id="1497" points="1709 242" /> </Inputs> <Outputs> <Output id="1504" /> </Outputs> <Properties> <displayName>C-ter TLR9 dimer binds HCQ</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1540" reactomeId="9678737" points="2049 441, 2049 440, 2105 447" position="2049 440" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1541" points="2131 398" /> <Input id="1542" points="2013 441" /> </Inputs> <Outputs> <Output id="1545" /> </Outputs> <Properties> <displayName>IFNAR1:TYK2 binds TYK2 inhibitors</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndEntitySetLink id="1543" points="1943 459, 1872 551, 1850 777" position="1872 551" lineWidth="0.5" lineColor="128 128 128"> <Inputs> <Input id="1542" /> </Inputs> <Outputs> <Output id="1301" /> </Outputs> </org.gk.render.EntitySetAndEntitySetLink> <org.gk.render.EntitySetAndEntitySetLink id="1544" points="1950 459, 1943 533" position="1946 496" lineWidth="0.5" lineColor="128 128 128"> <Inputs> <Input id="1542" /> </Inputs> <Outputs> <Output id="1314" /> </Outputs> </org.gk.render.EntitySetAndEntitySetLink> <org.gk.render.RenderableReaction id="1549" reactomeId="9678935" points="1966 822, 1964 823, 1979 896" position="1966 822" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1550" points="2113 895" /> <Input id="1301" points="1904 808" /> </Inputs> <Outputs> <Output id="1551" /> </Outputs> <Properties> <displayName>IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1554" reactomeId="9679787" points="864 403, 864 403, 926 403" position="864 403" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1555" points="823 369" /> <Input id="1556" points="826 415" /> </Inputs> <Outputs> <Output id="1557" /> </Outputs> <Properties> <displayName>HDAC1:2-containing complex binds HDAC2 Inhibitors</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1566" reactomeId="9691421" points="2185 219, 2185 219, 2184 255" position="2185 219" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1567" points="2185 182" /> <Input id="1568" points="2230 212" /> </Inputs> <Outputs> <Output id="1569" /> </Outputs> <Properties> <displayName>BTK binds BTK inhibitors</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1573" reactomeId="9647987" points="1532 754, 1531 752, 1456 785" position="1531 752" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1574" points="1550 693" /> <Input id="1575" points="1600 767" /> </Inputs> <Outputs> <Output id="1576" /> </Outputs> <Properties> <displayName>FNTB inhibitors bind FNTA:FNTB</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1582" reactomeId="9712274" points="316 780, 315 782, 375 783" position="315 782" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1583" points="261 762" /> <Input id="1584" points="256 794" /> </Inputs> <Outputs> <Output id="1585" /> </Outputs> <Properties> <displayName>NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1622" reactomeId="9732513" points="1077 786, 1077 786, 1127 786" position="1077 786" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1623" points="1015 809" /> <Input id="1624" points="1017 765" /> </Inputs> <Outputs> <Output id="1625" /> </Outputs> <Properties> <displayName>PI3K inhibitors bind to Activator:PI3K</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1626" reactomeId="9733063" points="906 565, 905 564, 949 564" position="905 564" lineWidth="1.0" isForDisease="true" lineColor="255 0 0" reactionType="Association"> <Inputs> <Input id="1627" points="834 529" /> <Input id="1628" points="853 587" /> </Inputs> <Outputs> <Output id="1629" /> </Outputs> <Properties> <displayName>XPO1 binds selinexor</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1635" reactomeId="9696179" points="2186 865, 2186 865, 2185 800" position="2186 865" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1550" points="2163 895" /> <Input id="1636" points="2257 892" /> </Inputs> <Outputs> <Output id="1637" /> </Outputs> <Properties> <displayName>IFNAR2:JAK1:STAT2 binds type 1 interferon analogs</displayName> </Properties> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process> |
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No pathways have been reviewed or authored by Diagram of Potential therapeutics for SARS (9679574)
