Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person PDCD1 binds PDCD1 inhibitors

Class:IdReaction:9679421
_displayNamePDCD1 binds PDCD1 inhibitors
_doReleaseTRUE
_timestamp2020-12-16 15:18:55
authored[InstanceEdit:9679442] Jassal, Bijay, 2020-03-24
compartment[Compartment:876] plasma membrane
[Compartment:984] extracellular region
created[InstanceEdit:9679442] Jassal, Bijay, 2020-03-24
definitionInhibition
edited[InstanceEdit:9679442] Jassal, Bijay, 2020-03-24
input[EntityWithAccessionedSequence:197604] PDCD1 [plasma membrane] [Homo sapiens]
[DefinedSet:9679406] PDCD1 inhibitors [extracellular region]
literatureReference[LiteratureReference:9685340] Camrelizumab: First Global Approval
[LiteratureReference:9679440] Characterization of the Anti-PD-1 Antibody REGN2810 and Its Antitumor Activity in Human PD-1 Knock-In Mice
[LiteratureReference:9685344] PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma
[LiteratureReference:9679417] Beyond the standard of care: a review of novel immunotherapy trials for the treatment of lung cancer
[LiteratureReference:9679427] Clinical development of mAbs to block the PD1 pathway as an immunotherapy for cancer
[LiteratureReference:9685346] PD-1/ PD-L1 blockade as a novel treatment for colorectal cancer
[LiteratureReference:9685306] An unexpected N-terminal loop in PD-1 dominates binding by nivolumab
modified[InstanceEdit:9679468] Jassal, Bijay, 2020-03-24
[InstanceEdit:9685307] Jassal, Bijay, 2020-04-23
[InstanceEdit:9685409] Jassal, Bijay, 2020-04-23
[InstanceEdit:9687446] D'Eustachio, Peter, 2020-05-08
[InstanceEdit:9688550] Jassal, Bijay, 2020-05-14
[InstanceEdit:9688754] Jassal, Bijay, 2020-05-14
[InstanceEdit:9709600] Jassal, Bijay, 2020-12-16
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePDCD1 binds PDCD1 inhibitors
output[Complex:9679420] PDCD1:PDCD1 inhibitors [plasma membrane] [Homo sapiens]
releaseDate2020-06-10
reviewed[InstanceEdit:9688552] Shoichet, Brian, 2020-05-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9679446] R-HSA-9679421.3
summation[Summation:9685298] Programmed cell death protein 1 (PDCD1, PD-1) is an immune c...
(hasEvent)[Pathway:389948] Co-inhibition by PD-1 [Homo sapiens]
[Pathway:9679191] Potential therapeutics for SARS [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by PDCD1 binds PDCD1 inhibitors (9679421)