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Details on Person JAK3 binds JAK3 inhibitors

Class:IdReaction:9679028
_displayNameJAK3 binds JAK3 inhibitors
_doReleaseTRUE
_timestamp2020-05-14 15:36:11
authored[InstanceEdit:9678968] Jassal, Bijay, 2020-03-23
compartment[Compartment:70101] cytosol
created[InstanceEdit:9678968] Jassal, Bijay, 2020-03-23
definitionInhibition
edited[InstanceEdit:9678968] Jassal, Bijay, 2020-03-23
input[EntityWithAccessionedSequence:451893] JAK3 [cytosol] [Homo sapiens]
[DefinedSet:9678772] JAK3 inhibitors [cytosol]
literatureReference[LiteratureReference:9678824] Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor
[LiteratureReference:9678541] Discovery and development of Janus kinase (JAK) inhibitors for inflammatory diseases
[LiteratureReference:9678987] Discovery of CP-690,550: a potent and selective Janus kinase (JAK) inhibitor for the treatment of autoimmune diseases and organ transplant rejection
[LiteratureReference:9686365] Tofacitinib: A Review in Rheumatoid Arthritis
[LiteratureReference:9686376] JAK3 inhibitors based on thieno[3,2-d]pyrimidine scaffold: design, synthesis and bioactivity evaluation for the treatment of B-cell lymphoma
modified[InstanceEdit:9679468] Jassal, Bijay, 2020-03-24
[InstanceEdit:9681847] Jassal, Bijay, 2020-04-06
[InstanceEdit:9686364] Jassal, Bijay, 2020-04-30
[InstanceEdit:9686368] Jassal, Bijay, 2020-04-30
[InstanceEdit:9687446] D'Eustachio, Peter, 2020-05-08
[InstanceEdit:9688550] Jassal, Bijay, 2020-05-14
[InstanceEdit:9688754] Jassal, Bijay, 2020-05-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameJAK3 binds JAK3 inhibitors
output[Complex:9678869] JAK3:JAK3 inhibitors [cytosol] [Homo sapiens]
releaseDate2020-06-10
reviewed[InstanceEdit:9688552] Shoichet, Brian, 2020-05-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9679181] R-HSA-9679028.2
summation[Summation:9686361] Janus Kinase 3 (JAK3) binds and is inhibited by several smal...
(hasEvent)[Pathway:1266695] Interleukin-7 signaling [Homo sapiens]
[Pathway:6785807] Interleukin-4 and Interleukin-13 signaling [Homo sapiens]
[Pathway:8985947] Interleukin-9 signaling [Homo sapiens]
[Pathway:9020558] Interleukin-2 signaling [Homo sapiens]
[Pathway:9679191] Potential therapeutics for SARS [Homo sapiens]
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No pathways have been reviewed or authored by JAK3 binds JAK3 inhibitors (9679028)