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Details on Person S1PR1 binds S1PR1 agonists

Class:IdReaction:9678854
_displayNameS1PR1 binds S1PR1 agonists
_doReleaseTRUE
_timestamp2021-03-04 10:32:22
authored[InstanceEdit:9678968] Jassal, Bijay, 2020-03-23
compartment[Compartment:876] plasma membrane
[Compartment:984] extracellular region
created[InstanceEdit:9678968] Jassal, Bijay, 2020-03-23
definitionAgonist
edited[InstanceEdit:9678968] Jassal, Bijay, 2020-03-23
input[EntityWithAccessionedSequence:419340] S1PR1 [plasma membrane] [Homo sapiens]
[DefinedSet:9678899] S1PR1 agonists [extracellular region]
literatureReference[LiteratureReference:9678874] Metabolism and Disposition of Siponimod, a Novel Selective S1P1/S1P5 Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism
[LiteratureReference:9678780] Discovery of BAF312 (Siponimod), a Potent and Selective S1P Receptor Modulator
[LiteratureReference:9684964] Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis
[LiteratureReference:9717114] Ozanimod (RPC1063) is a potent sphingosine-1-phosphate receptor-1 (S1P1 ) and receptor-5 (S1P5 ) agonist with autoimmune disease-modifying activity
modified[InstanceEdit:9679468] Jassal, Bijay, 2020-03-24
[InstanceEdit:9681847] Jassal, Bijay, 2020-04-06
[InstanceEdit:9684954] Jassal, Bijay, 2020-04-22
[InstanceEdit:9687446] D'Eustachio, Peter, 2020-05-08
[InstanceEdit:9688550] Jassal, Bijay, 2020-05-14
[InstanceEdit:9688754] Jassal, Bijay, 2020-05-14
[InstanceEdit:9717106] Stephan, Ralf, 2021-03-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameS1PR1 binds S1PR1 agonists
output[Complex:9678686] S1PR1:S1PR1 agonists [plasma membrane] [Homo sapiens]
releaseDate2020-06-10
reviewed[InstanceEdit:9688552] Shoichet, Brian, 2020-05-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9679155] R-HSA-9678854.3
summation[Summation:9684956] Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid th...
(hasEvent)[Pathway:419408] Lysosphingolipid and LPA receptors [Homo sapiens]
[Pathway:9679191] Potential therapeutics for SARS [Homo sapiens]
(precedingEvent)[Reaction:9690449] S1PR1 bind S1P [Homo sapiens]
(updatedInstance)[_UpdateTracker:9776229] Update Tracker - [Reaction:9678854] S1PR1 binds S1PR1 agonists - v77:[addLiteratureReference, modifyText]
[_UpdateTracker:9776794] Update Tracker - [Reaction:9678854] S1PR1 binds S1PR1 agonists - v74:[modifyText]
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No pathways have been reviewed or authored by S1PR1 binds S1PR1 agonists (9678854)
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