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Details on Person Factor VIIIa-mimetic cofactor activity of a bispecific antibody to factors IX/IXa and X/Xa, emicizumab, depends on its ability to bridge the antigens
| Class:Id | LiteratureReference:9678380 |
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| _displayName | Factor VIIIa-mimetic cofactor activity of a bispecific antibody to factors IX/IXa and X/Xa, emicizumab, depends on its ability to bridge the antigens |
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| _timestamp | 2020-03-19 03:08:43 |
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| author | [Person:9678393] Kitazawa, Takehisa
[Person:9678381] Esaki, Keiko
[Person:9678388] Tachibana, Tatsuhiko
[Person:9678392] Ishii, Shinya
[Person:9678377] Soeda, Tetsuhiro
[Person:9678385] Muto, Atsushi
[Person:9678382] Kawabe, Yoshiki
[Person:9678378] Igawa, Tomoyuki
[Person:9678383] Tsunoda, Hiroyuki
[Person:9665859] Nogami, Keiji
[Person:9667150] Shima, Midori
[Person:9678389] Hattori, Kunihiro |
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| created | [InstanceEdit:9678391] Shamovsky, Veronica, 2020-03-19 |
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| journal | Thromb. Haemost. |
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| pages | 1348-1357 |
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| pubMedIdentifier | 28451690 |
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| title | Factor VIIIa-mimetic cofactor activity of a bispecific antibody to factors IX/IXa and X/Xa, emicizumab, depends on its ability to bridge the antigens |
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| volume | 117 |
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| year | 2017 |
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| (literatureReference) | [Summation:9678403] Emicizumab (also known as ACE910, trade name Hemlibra) is a ...
[Summation:9678433] In healthy individuals, coagulation factor VIII, in its acti...
[Reaction:9678390] Factor IXa binds emicizumab [Homo sapiens]
[Reaction:9678434] factor X -> factor Xa + factor X activation peptide (emicizumab:FIXa catalyst) [Homo sapiens]
[CatalystActivityReference:9678435] serine-type endopeptidase activity of factor IXa:emicizumab [plasma membrane] Factor VIIIa-mimetic cofactor activity of a bispecific antibody to factors IX/IXa and X/Xa, emicizumab, depends on its ability to bridge the antigens |
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