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Details on Person MLL1,MLL2 methylate H3K4 at MYF5 gene promoter and enhancers

Class:Id	Reaction:9678077
_displayName	MLL1,MLL2 methylate H3K4 at MYF5 gene promoter and enhancers
_doRelease	FALSE
_timestamp	2020-03-12 19:42:17
catalystActivity	[CatalystActivity:9678073] histone H3K4 methyltransferase activity of MYF5 gene:Nucleosome:Me2aR10,R13,R22,R37-PAX7:MLL1,MLL2 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9678076] Orlic-Milacic, Marija, 2020-03-12
inferredFrom	[Reaction:9678088] MLL1,MLL2 methylate H3K4 at Myf5 gene promoter and enhancers [Mus musculus]
input	[Complex:9678055] MYF5 gene:Nucleosome:Me2aR10,R13,R22,R37-PAX7:MLL1,MLL2 [nucleoplasm] [Homo sapiens] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm]
isChimeric	FALSE
modified	[InstanceEdit:9678093] Orlic-Milacic, Marija, 2020-03-12
name	MLL1,MLL2 methylate H3K4 at MYF5 gene promoter and enhancers
output	[Complex:9678078] MYF5 gene:Nucleosome:Me2aR10,R13,R22,R37-PAX7:MLL1,MLL2 [nucleoplasm] [Homo sapiens] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm]
precedingEvent	[Reaction:9678053] Methylated PAX7 recruites MLL1,MLL2 to the MYF5 gene promoter and enhancers [Homo sapiens] [Reaction:9678022] CARM1 methylates PAX7 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9678083] R-HSA-9678077.1
summation	[Summation:9678075] Based on findings in a mouse model system, the MLL1 and MLL2...
(hasEvent)	[Pathway:9677821] MLLs regulate transcription of myogenesis genes [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9678079] MYF5 gene expression in stimulated by PAX7 and MLL1,MLL2 [Homo sapiens]
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No pathways have been reviewed or authored by MLL1,MLL2 methylate H3K4 at MYF5 gene promoter and enhancers (9678077)