Query author contributions in Reactome
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Details on Person Based on findings in a mouse model system, transcription of ...
| Class:Id | Summation:9678074 |
|---|---|
| _displayName | Based on findings in a mouse model system, transcription of ... |
| _timestamp | 2020-03-12 19:35:25 |
| created | [InstanceEdit:9678076] Orlic-Milacic, Marija, 2020-03-12 |
| literatureReference | [LiteratureReference:9678018] Carm1 regulates Pax7 transcriptional activity through MLL1/2 recruitment during asymmetric satellite stem cell divisions [LiteratureReference:9678065] Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex |
| text | Based on findings in a mouse model system, transcription of the MYF5 gene is directly stimulated by PAX7 and the MLL1 and MLL2-mediated H3K4 trimethylation of nucleosomes at the MYF5 gene promoter and enhancers (McKinnell et al. 2008, Kawabe et al. 2012). The MYF5 gene encodes a transcription factor Myogenic factor 5, which promotes mygenesis by positively regulating transcription of muscle cell-specific genes. |
| (summation) | [BlackBoxEvent:9678079] MYF5 gene expression in stimulated by PAX7 and MLL1,MLL2 [Homo sapiens] |
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No pathways have been reviewed or authored by Based on findings in a mouse model system, transcription of ... (9678074)
