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Details on Person Methylated PAX7 recruites MLL1,MLL2 to the MYF5 gene promoter and enhancers

Class:Id	Reaction:9678053
_displayName	Methylated PAX7 recruites MLL1,MLL2 to the MYF5 gene promoter and enhancers
_doRelease	FALSE
_timestamp	2022-04-24 11:53:38
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9678052] Orlic-Milacic, Marija, 2020-03-12
inferredFrom	[Reaction:9678050] Methylated Pax7 recruits MLL1,MLL2 to Myf5 gene promoter and enhancers [Mus musculus]
input	[EntityWithAccessionedSequence:9678016] Me2aR10,R13,R22,R37-PAX7 [nucleoplasm] [Homo sapiens] [DefinedSet:9678056] MLL1,MLL2 [nucleoplasm] [Homo sapiens] [Complex:9678049] MYF5 gene:Nucleosome [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9772798] Pax3/7BP is a Pax7- and Pax3-binding protein that regulates the proliferation of muscle precursor cells by an epigenetic mechanism
modified	[InstanceEdit:9772814] Orlic-Milacic, Marija, 2022-04-24
name	Methylated PAX7 recruites MLL1,MLL2 to the MYF5 gene promoter and enhancers
output	[Complex:9678055] MYF5 gene:Nucleosome:Me2aR10,R13,R22,R37-PAX7:MLL1,MLL2 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9678022] CARM1 methylates PAX7 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9678062] R-HSA-9678053.1
summation	[Summation:9678051] Based on studies in a mouse model system, PAX7, methylated b...
(hasEvent)	[Pathway:9677821] MLLs regulate transcription of myogenesis genes [Homo sapiens]
(precedingEvent)	[Reaction:9678077] MLL1,MLL2 methylate H3K4 at MYF5 gene promoter and enhancers [Homo sapiens]
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No pathways have been reviewed or authored by Methylated PAX7 recruites MLL1,MLL2 to the MYF5 gene promoter and enhancers (9678053)