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Details on Person H3K4 trimethylation at CARM1 gene promoter

Class:Id	Reaction:9677863
_displayName	H3K4 trimethylation at CARM1 gene promoter
_doRelease	FALSE
_timestamp	2020-03-11 19:04:49
catalystActivity	[CatalystActivity:9677861] histone H3K4 methyltransferase activity of (MLL1,MLL2):CARM1 gene:Nucleosome [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9677859] Orlic-Milacic, Marija, 2020-03-11
input	[Complex:9677845] (MLL1,MLL2):CARM1 gene:Nucleosome [nucleoplasm] [Homo sapiens] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm] [SimpleEntity:77087] AdoMet [nucleoplasm]
isChimeric	FALSE
literatureReference	[LiteratureReference:9677843] WDR5-Myc axis promotes the progression of glioblastoma and neuroblastoma by transcriptional activating CARM1
modified	[InstanceEdit:9677880] Orlic-Milacic, Marija, 2020-03-11
name	H3K4 trimethylation at CARM1 gene promoter
output	[Complex:9677860] (MLL1,MLL2):CARM1 gene:Nucleosome-H3K4me3 [nucleoplasm] [Homo sapiens] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm] [SimpleEntity:77502] AdoHcy [nucleoplasm]
precedingEvent	[Reaction:9677837] WDR5 binds the promoter of the CARM1 gene [Homo sapiens] [Reaction:9675026] Formation of the MLL1 complex [Homo sapiens] [Reaction:9676255] Formation of the MLL2 complex [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9677864] R-HSA-9677863.1
summation	[Summation:9677869] Un unspecified MLL complex, probably MLL1 or MLL2, recruited...
(hasEvent)	[Pathway:9677821] MLLs regulate transcription of myogenesis genes [Homo sapiens]
(precedingEvent)	[Reaction:9677872] MYC binds CARM1 gene promoter [Homo sapiens]
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No pathways have been reviewed or authored by H3K4 trimethylation at CARM1 gene promoter (9677863)