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Details on Person WDR5 binds the promoter of the CARM1 gene

Class:Id	Reaction:9677837
_displayName	WDR5 binds the promoter of the CARM1 gene
_doRelease	FALSE
_timestamp	2020-03-11 18:26:55
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9677847] Orlic-Milacic, Marija, 2020-03-11
input	[CandidateSet:9677841] (MLL1,MLL2) [nucleoplasm] [Homo sapiens] [Complex:9677862] CARM1 gene:Nucleosome [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9677843] WDR5-Myc axis promotes the progression of glioblastoma and neuroblastoma by transcriptional activating CARM1
modified	[InstanceEdit:9677868] Orlic-Milacic, Marija, 2020-03-11
name	WDR5 binds the promoter of the CARM1 gene
output	[Complex:9677845] (MLL1,MLL2):CARM1 gene:Nucleosome [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9675026] Formation of the MLL1 complex [Homo sapiens] [Reaction:9675214] Formation of the WRAD complex [Homo sapiens] [BlackBoxEvent:9818576] Cleaved KMT2A dimers translocate to the nucleus [Homo sapiens] [Reaction:9676255] Formation of the MLL2 complex [Homo sapiens] [Reaction:9675214] Formation of the WRAD complex [Homo sapiens] [BlackBoxEvent:9818578] Cleaved KMT2B dimers translocate to the nucleus [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9677855] R-HSA-9677837.1
summation	[Summation:9677844] WDR5, as part of an unspecified MLL complex with histone H3K...
(hasEvent)	[Pathway:9677821] MLLs regulate transcription of myogenesis genes [Homo sapiens]
(precedingEvent)	[Reaction:9677863] H3K4 trimethylation at CARM1 gene promoter [Homo sapiens]
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No pathways have been reviewed or authored by WDR5 binds the promoter of the CARM1 gene (9677837)