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Details on Person JAK1 is phosphorylated by an unknown kinase in response to C...

Class:IdSummation:9677133
_displayNameJAK1 is phosphorylated by an unknown kinase in response to C...
_timestamp2020-05-10 06:19:28
created[InstanceEdit:9677153] May, Bruce, 2020-02-28
modified[InstanceEdit:9677590] May, Bruce, 2020-03-09
[InstanceEdit:9677884] May, Bruce, 2020-03-12
[InstanceEdit:9687567] May, Bruce, 2020-05-10
textJAK1 is phosphorylated by an unknown kinase in response to CSF3 binding CSF3R (Nicholson et al. 1994, Tian et al. 1994, Marino and Roguin 2008). Phosphorylated JAK1 is required for subsequent phosphorylation of CSF3R (Shimoda et al. 1997, inferred from mouse homologs). The SRC-related protein kinase LYN is constitutively associated with CSF3R (Corey et al. 1994).
(summation)[BlackBoxEvent:9674546] CSF3 dimer:2xCSF3R:LYN:JAK1 induces phosphorylation of JAK1 [Homo sapiens]
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