Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person HOXA2,(HOXA10) gene expression is positively regulated by MLL1 and negatively regulated by PRMT6

Class:Id	BlackBoxEvent:9677039
_displayName	HOXA2,(HOXA10) gene expression is positively regulated by MLL1 and negatively regulated by PRMT6
_doRelease	FALSE
_timestamp	2020-03-10 13:50:33
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9677038] Orlic-Milacic, Marija, 2020-02-25
input	[CandidateSet:9675055] HOXA2 gene,(HOXA10 gene) [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5205806] PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation
modified	[InstanceEdit:9677677] Orlic-Milacic, Marija, 2020-03-10
name	HOXA2,(HOXA10) gene expression is positively regulated by MLL1 and negatively regulated by PRMT6
output	[CandidateSet:9675054] HOXA2,(HOXA10) [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9675029] MLL1 complex methylates lysine K4 of histone H3 on target gene promoters [Homo sapiens] [Reaction:9675028] WDR5 binds the N-tail of histone H3 at target gene promoters [Homo sapiens] [Reaction:9675030] PRMT6 methylates R2me1 of histone H3 at target gene promoters [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9677036] Positive gene expression regulation by 'HOXA2 gene,(HOXA10 gene):H3K4Me3-Nucleosome:MLL1 complex [nucleoplasm]' [NegativeGeneExpressionRegulation:9677037] Negative gene expression regulation by 'HOXA2,(HOXA10) gene:H3R2Me2-nucleosome:PRMT6 [nucleoplasm]'
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9677041] R-HSA-9677039.1
summation	[Summation:9677040] The HOXA2 gene transcription and likely HOXA10 gene transcri...
(hasEvent)	[Pathway:9677820] MLLs regulate transcription of homeobox genes [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by HOXA2,(HOXA10) gene expression is positively regulated by MLL1 and negatively regulated by PRMT6 (9677039)