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Details on Person After phosphorylation while bound to phospho-CSF3R at the pl...

Class:IdSummation:9676909
_displayNameAfter phosphorylation while bound to phospho-CSF3R at the pl...
_timestamp2020-05-10 06:19:21
created[InstanceEdit:9676913] May, Bruce, 2020-02-23
modified[InstanceEdit:9677884] May, Bruce, 2020-03-12
[InstanceEdit:9687567] May, Bruce, 2020-05-10
textAfter phosphorylation while bound to phospho-CSF3R at the plasma membrane, p-STAT1,3,5 dissociates from CSF3R prior to dimerizing and transiting to the nucleus (Tian et al. 1994, Tian et al. 1996, Ward et al. 1999, also inferred from mouse homologs).
(summation)[Reaction:9674563] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 dissociates yielding CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 and p-Y-STAT1,3,5 [Homo sapiens]
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