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Details on Person SET1A complex [nucleoplasm]

Class:Id	Complex:9676258
_displayName	SET1A complex [nucleoplasm]
_timestamp	2020-02-11 15:34:21
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9676262] Orlic-Milacic, Marija, 2020-02-11
hasComponent	[Complex:9675213] WRAD complex [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:1629838] WDR5 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:1629834] ASH2L [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5669104] DPY30 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:1629836] RBBP5 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:3239027] SETD1A [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9676266] The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases
name	SET1A complex SETD1A:WRAD complex SETD1A:WDR5:RBBP5:ASH2L:DPY30
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9676279] R-HSA-9676258.1
(activeUnit)	[PositiveGeneExpressionRegulation:9818216] Positive gene expression regulation by 'SET1A complex:SET1A target genes with H3K4 methylated nucleosomes [nucleoplasm]' [CatalystActivity:9818220] histone H3K4 methyltransferase activity of SET1A complex:SET1A target genes:Nucleosomes [nucleoplasm]
(hasComponent)	[Complex:9818221] SET1A complex:SET1A target genes:Nucleosomes [nucleoplasm] [Homo sapiens] [Complex:9821477] SET1A complex:WDR82:CXXC1 [nucleoplasm] [Homo sapiens] [Complex:9983695] SET1A complex:Me-R20-LANA1 Oligomer:HHV8 Circular Episome:Condensed prophase chromosome [nucleoplasm] [Homo sapiens]
(hasMember)	[CandidateSet:5244738] Core MLL complex [nucleoplasm] [Homo sapiens]
(input)	[Reaction:9818225] SET1A complex binds target gene loci [Homo sapiens] [Reaction:9821475] CXXC1 and WDR82 bind SET1A complex [Homo sapiens] [Reaction:9983687] LANA1 recruits the SET1A complex [Homo sapiens]
(output)	[Reaction:9676257] Formation of the SET1A complex [Homo sapiens]
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No pathways have been reviewed or authored by SET1A complex [nucleoplasm] (9676258)