Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Rothfels, Karen, 2020-02-08

Class:IdInstanceEdit:9676121
_displayNameRothfels, Karen, 2020-02-08
_timestamp2020-02-08 16:56:35
author[Person:1226097] Rothfels, Karen
dateTime2020-02-08 16:56:32
(modified)[Summation:186784] Phosphatidylinositol 3'-kinases (PI3Ks) are a family of enzy...
[Summation:382616] SOS is the guanine nucleotide exchange factor (GEF) for RAS....
[Reaction:9672164] GRB2:SOS1 complex binds to mutant PDGFR receptor [Homo sapiens]
[Reaction:9672172] PI3-kinase binds to mutant PDGFR receptor [Homo sapiens]
[Reaction:9672177] PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of mutant PDGFR [Homo sapiens]
[Summation:9673733] SOS-mediated exchange of GTP for GDP on RAS is predicted to ...
[Summation:9673736] Gain-of-function mutants of PDGFRA bind to phosphatidylinosi...
[Summation:9673737] MAP kinase signaling is activated downstream of gain-of-func...
[Summation:9673739] In addition to activating missense mutations and in-frame de...
[Summation:9673740] PDGFRA is a type III transmembrane receptor tyrosine kinase...
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No pathways have been reviewed or authored by Rothfels, Karen, 2020-02-08 (9676121)