Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Rothfels, Karen, 2020-02-07

Class:IdInstanceEdit:9676111
_displayNameRothfels, Karen, 2020-02-07
_timestamp2020-02-07 19:02:54
author[Person:1226097] Rothfels, Karen
dateTime2020-02-07 19:02:46
(modified)[Summation:186777] PDGF dimer binds two receptors simultaneously. The receptors...
[Summation:186790] Receptor dimerisation is key event in PDGF receptor activati...
[Pathway:9671555] Signaling by PDGFR in disease [Homo sapiens]
[Reaction:9672158] GRB2:SOS1 complex binds to PDGFRA extracellular domain dimers [Homo sapiens]
[Reaction:9672159] STAT binds to p-11Y PDGFRA extracellular domain dimers [Homo sapiens]
[Reaction:9672162] PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of PDGFRA extracellular domain dimers [Homo sapiens]
[Reaction:9672163] SOS-mediated nucleotide exchange on RAS downstream of PDGFRA extracellular domain dimers [Homo sapiens]
[Reaction:9672164] GRB2:SOS1 complex binds to mutant PDGFR receptor [Homo sapiens]
[Reaction:9672168] Ligand-independent dimerization of PDGFR mutants [Homo sapiens]
[Reaction:9672170] SOS-mediated nucleotide exchange of RAS downstream of mutant PDGFR receptors [Homo sapiens]
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No pathways have been reviewed or authored by Rothfels, Karen, 2020-02-07 (9676111)