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Details on Person Distinct regions of the granulocyte colony-stimulating factor receptor are required for tyrosine phosphorylation of the signaling molecules JAK2, Stat3, and p42, p44MAPK
| Class:Id | LiteratureReference:9676040 |
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| _displayName | Distinct regions of the granulocyte colony-stimulating factor receptor are required for tyrosine phosphorylation of the signaling molecules JAK2, Stat3, and p42, p44MAPK |
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| _timestamp | 2020-02-07 03:40:17 |
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| author | [Person:9674570] Nicholson, S E
[Person:9674975] Novak, U
[Person:5602801] Ziegler, S F
[Person:9674569] Layton, J E |
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| created | [InstanceEdit:9676039] May, Bruce, 2020-02-07 |
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| journal | Blood |
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| pages | 3698-704 |
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| pubMedIdentifier | 7579336 |
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| title | Distinct regions of the granulocyte colony-stimulating factor receptor are required for tyrosine phosphorylation of the signaling molecules JAK2, Stat3, and p42, p44MAPK |
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| volume | 86 |
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| year | 1995 |
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| (literatureReference) | [Reaction:9674908] p-Y-Jak1,2 phosphorylates Stat1,3,5 in Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2:Stat1,3,5 [Mus musculus]
[Reaction:9674931] Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2:p-Y-Stat1,3,5 dissociates yielding Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 and p-Y-Stat1,3,5 [Mus musculus]
[BlackBoxEvent:9676072] Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1 binds and activates Jak2, Syk, Hck, and Tyk2 [Mus musculus]
[BlackBoxEvent:9676907] p-Y-Stat1,3,5 dimer translocates from the cytosol to the nucleus [Mus musculus] |
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