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Details on Person May, Bruce, 2020-01-29
| Class:Id | InstanceEdit:9675009 |
| _displayName | May, Bruce, 2020-01-29 |
| _timestamp | 2020-01-29 11:03:05 |
| author | [Person:203835] May, Bruce |
| dateTime | 2020-01-29 11:02:57 |
| (authored) | [BlackBoxEvent:9676071] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 binds and activates JAK2, TYK2, SYK, and HCK [Homo sapiens] [BlackBoxEvent:9676072] Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1 binds and activates Jak2, Syk, Hck, and Tyk2 [Mus musculus] |
| (edited) | [BlackBoxEvent:9676071] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 binds and activates JAK2, TYK2, SYK, and HCK [Homo sapiens] [BlackBoxEvent:9676072] Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1 binds and activates Jak2, Syk, Hck, and Tyk2 [Mus musculus] |
| (modified) | [BlackBoxEvent:9674546] CSF3 dimer:2xCSF3R:LYN:JAK1 induces phosphorylation of JAK1 [Homo sapiens] [Reaction:9674558] p-Y-JAK1 phosphorylates CSF3R in CSF3 dimer:2xCSF3R:LYN:p-Y-JAK1 [Homo sapiens] [Reaction:9674562] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds STAT1,3,5 [Homo sapiens] [Reaction:9674563] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 dissociates yielding CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 and p-Y-STAT1,3,5 [Homo sapiens] [BlackBoxEvent:9674808] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-TYK2 binds and phosphorylates SHC1, GRB2, GAB2, and PTPN11 (SHP2) [Homo sapiens] [BlackBoxEvent:9674812] PTPN11 is phosphorylated in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC1:GRB2:PTPN11 [Homo sapiens] [Summation:9674828] CSF3 (G-CSF) signaling activates ERKs (ERK1, ERK2) via RAS. ... |
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No pathways have been reviewed or authored by May, Bruce, 2020-01-29 (9675009)