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Details on Person p-Y-Jak1 phosphorylates Csf3r in Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2

Class:Id	Reaction:9674921
_displayName	p-Y-Jak1 phosphorylates Csf3r in Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2
_doRelease	TRUE
_timestamp	2020-12-12 08:36:09
authored	[InstanceEdit:9674838] May, Bruce, 2020-01-27
catalystActivity	[CatalystActivity:9674918] protein tyrosine kinase activity of Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9674890] May, Bruce, 2020-01-29
edited	[InstanceEdit:9674838] May, Bruce, 2020-01-27
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [Complex:9674961] Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1 [plasma membrane] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9674955] Unidirectional cross-phosphorylation between the granulocyte colony-stimulating factor and interleukin 3 receptors [LiteratureReference:9674969] Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colony-stimulating factor
modified	[InstanceEdit:9676064] May, Bruce, 2020-02-07 [InstanceEdit:9676080] May, Bruce, 2020-02-07 [InstanceEdit:9677157] May, Bruce, 2020-02-28 [InstanceEdit:9709305] May, Bruce, 2020-12-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-Y-Jak1 phosphorylates Csf3r in Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2
output	[Complex:9674894] Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1 [plasma membrane] [Mus musculus] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
releaseDate	2021-03-23
reviewed	[InstanceEdit:9709304] Touw, Ivo P, 2020-12-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9674989] R-MMU-9674921.2
summation	[Summation:9677137] The cytosolic domain of Csf3r is phosphorylated (Pan et al. ...
(inferredFrom)	[Reaction:9674558] p-Y-JAK1 phosphorylates CSF3R in CSF3 dimer:2xCSF3R:LYN:p-Y-JAK1 [Homo sapiens]
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No pathways have been reviewed or authored by p-Y-Jak1 phosphorylates Csf3r in Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2 (9674921)