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Details on Person Tyrosine-dependent and -independent mechanisms of STAT3 activation by the human granulocyte colony-stimulating factor (G-CSF) receptor are differentially utilized depending on G-CSF concentration
| Class:Id | LiteratureReference:9674885 |
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| _displayName | Tyrosine-dependent and -independent mechanisms of STAT3 activation by the human granulocyte colony-stimulating factor (G-CSF) receptor are differentially utilized depending on G-CSF concentration |
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| _timestamp | 2020-01-29 09:17:16 |
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| author | [Person:9674941] Ward, A C
[Person:9674950] Hermans, M H
[Person:2672086] Smith, L
[Person:9674979] van Aesch, Y M
[Person:9674892] Schelen, A M
[Person:9674913] Antonissen, C
[Person:9027141] Touw, I P |
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| created | [InstanceEdit:9674890] May, Bruce, 2020-01-29 |
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| journal | Blood |
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| pages | 113-24 |
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| pubMedIdentifier | 9864153 |
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| title | Tyrosine-dependent and -independent mechanisms of STAT3 activation by the human granulocyte colony-stimulating factor (G-CSF) receptor are differentially utilized depending on G-CSF concentration |
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| volume | 93 |
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| year | 1999 |
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| (literatureReference) | [Reaction:9674542] p-Y-STAT1,3,5 dimerize [Homo sapiens]
[BlackBoxEvent:9674550] p-Y-STAT1,3,5 dimer translocates from the cytosol to the nucleoplasm [Homo sapiens]
[Reaction:9674562] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds STAT1,3,5 [Homo sapiens]
[Reaction:9674563] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 dissociates yielding CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 and p-Y-STAT1,3,5 [Homo sapiens]
[Reaction:9674567] p-Y-JAK1,2 phosphorylates STAT1,3,5 in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-Y-JAK2:p-TYK2 [Homo sapiens] |
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