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Details on Person In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship

Class:IdLiteratureReference:9674233
_displayNameIn vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship
_timestamp2020-01-13 03:50:33
author[Person:9674227] Mendel, Dirk B
[Person:9652248] Laird, A Douglas
[Person:9674225] Xin, Xiaohua
[Person:9674243] Louie, Sharianne G
[Person:6800518] Christensen, James G
[Person:9674230] Li, Guangmin
[Person:9674232] Schreck, Randall E
[Person:9674237] Abrams, Tinya J
[Person:9674236] Ngai, Theresa J
[Person:9674240] Lee, Leslie B
[Person:9674229] Murray, Lesley J
[Person:9674238] Carver, Jeremy
[Person:9674239] Chan, Emily
[Person:9674226] Moss, Katherine G
[Person:9674241] Haznedar, Joshua O
[Person:9674244] Sukbuntherng, Juthamas
[Person:9674228] Blake, Robert A
[Person:201393] Sun, L
[Person:201392] Tang, C
[Person:9674235] Miller, Todd
[Person:9674234] Shirazian, Sheri
[Person:201394] McMahon, G
[Person:9674242] Cherrington, Julie M
created[InstanceEdit:9674231] Rothfels, Karen, 2020-01-13
journalClin. Cancer Res.
pages327-37
pubMedIdentifier12538485
titleIn vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship
volume9
year2003
(literatureReference)[BlackBoxEvent:186773] PDGF dimer binds two receptors simultaneously [Homo sapiens]
[Reaction:9674095] PDGFRs bind type II TKI [Homo sapiens]
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No pathways have been reviewed or authored by In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship (9674233)