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Details on Person USP30 deubiquitinates ATM dimer:Ub-p-PEX5

Class:Id	Reaction:9674127
_displayName	USP30 deubiquitinates ATM dimer:Ub-p-PEX5
_doRelease	TRUE
_timestamp	2020-04-07 10:37:45
authored	[InstanceEdit:9673101] Varusai, Thawfeek, 2020-01-06
catalystActivity	[CatalystActivity:9674130] deubiquitinase activity of ATM dimer:Ub-p-PEX5:USP30 [peroxisomal membrane]
compartment	[Compartment:17947] peroxisomal membrane
created	[InstanceEdit:9674147] Varusai, Thawfeek, 2020-01-10
edited	[InstanceEdit:9674460] Varusai, Thawfeek, 2020-01-13
input	[Complex:9674136] ATM dimer:Ub-p-PEX5:USP30 [peroxisomal membrane] [Homo sapiens] [SimpleEntity:29356] H2O [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9674146] Deubiquitinating enzyme USP30 maintains basal peroxisome abundance by regulating pexophagy [LiteratureReference:9674138] New aspects of USP30 biology in the regulation of pexophagy [LiteratureReference:9674128] USP30: protector of peroxisomes and mitochondria
modified	[InstanceEdit:9674152] Varusai, Thawfeek, 2020-01-10 [InstanceEdit:9674460] Varusai, Thawfeek, 2020-01-13 [InstanceEdit:9677120] Matthews, Lisa, 2020-02-27 [InstanceEdit:9682019] Varusai, Thawfeek, 2020-04-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	USP30 deubiquitinates ATM dimer:Ub-p-PEX5
output	[Complex:9665178] ATM dimer:p-PEX5 [peroxisomal membrane] [Homo sapiens] [DefinedSet:113595] Ub [cytosol] [Homo sapiens]
precedingEvent	[Reaction:9674131] USP30 binds ATM dimer:Ub-p-PEX5 [Homo sapiens] [Reaction:9664888] ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 [Homo sapiens]
releaseDate	2020-03-17
reviewed	[InstanceEdit:9682017] Metzakopian, Emmanouil, 2019-10-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9674149] R-HSA-9674127.3
summation	[Summation:9674129] The deubiquitinase, Ubiquitin carboxyl-terminal hydrolase 30...
(hasEvent)	[Pathway:9664873] Pexophagy [Homo sapiens]
(precedingEvent)	[Reaction:9664888] ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 [Homo sapiens]
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No pathways have been reviewed or authored by USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (9674127)