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Details on Person p-12Y-GOLGA4(1-411)-PDGFRB(527-1106) fusion [plasma membrane]

Class:Id	EntityWithAccessionedSequence:9673642
_displayName	p-12Y-GOLGA4(1-411)-PDGFRB(527-1106) fusion [plasma membrane]
_timestamp	2023-03-30 17:41:43
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9673643] Rothfels, Karen, 2020-01-08
disease	[Disease:1614677] myelodysplastic myeloproliferative cancer
endCoordinate	411
hasModifiedResidue	[FragmentInsertionModification:9673591] Insertion of residues 527 to 1106 at 412 from UniProt:P09619 PDGFRB [ModifiedResidue:186818] O4'-phospho-L-tyrosine at 1009 [ModifiedResidue:186774] O4'-phospho-L-tyrosine at 1021 [ModifiedResidue:186804] O4'-phospho-L-tyrosine at 579 [ModifiedResidue:186781] O4'-phospho-L-tyrosine at 581 [ModifiedResidue:186807] O4'-phospho-L-tyrosine at 716 [ModifiedResidue:186768] O4'-phospho-L-tyrosine at 740 [ModifiedResidue:186814] O4'-phospho-L-tyrosine at 751 [ModifiedResidue:186810] O4'-phospho-L-tyrosine at 763 [ModifiedResidue:186793] O4'-phospho-L-tyrosine at 771 [ModifiedResidue:186788] O4'-phospho-L-tyrosine at 775 [ModifiedResidue:186808] O4'-phospho-L-tyrosine at 778 [ModifiedResidue:389092] O4'-phospho-L-tyrosine at 857
literatureReference	[LiteratureReference:9673510] Fusion of PDGFRB to two distinct loci at 3p21 and a third at 12q13 in imatinib-responsive myeloproliferative neoplasms
modified	[InstanceEdit:9676330] Rothfels, Karen, 2020-02-12 [InstanceEdit:9832399] Orlic-Milacic, Marija, 2023-03-30
name	p-12Y-GOLGA4(1-411)-PDGFRB(527-1106) fusion
referenceEntity	[ReferenceGeneProduct:55786] UniProt:Q13439 GOLGA4 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9673644] R-HSA-9673642.2
startCoordinate	1
(hasComponent)	[Complex:9673705] p-12Y GOLGA4(1-411)-PDGFRB(527-1106) fusion dimer [plasma membrane] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9905699] Update Tracker - [EntityWithAccessionedSequence:9673642] p-12Y-GOLGA4(1-411)-PDGFRB(527-1106) fusion [plasma membrane] - v85:[modifyName]
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No pathways have been reviewed or authored by p-12Y-GOLGA4(1-411)-PDGFRB(527-1106) fusion [plasma membrane] (9673642)