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Details on Person PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

Class:IdLiteratureReference:9673553
_displayNamePDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas
_timestamp2020-01-08 22:23:48
author[Person:9673554] Ozawa, Tatsuya
[Person:9673551] Brennan, Cameron W
[Person:1247490] Wang, L
[Person:9673555] Squatrito, Massimo
[Person:2574831] Sasayama, Takashi
[Person:3787976] Nakada, Mitsutoshi
[Person:2318753] Huse, Jason T
[Person:9673556] Pedraza, Alicia
[Person:9673552] Utsuki, Satoshi
[Person:9673547] Yasui, Yoshie
[Person:9673545] Tandon, Adesh
[Person:9673548] Fomchenko, Elena I
[Person:9673546] Oka, Hidehiro
[Person:3215414] Levine, Ross L
[Person:9673550] Fujii, Kiyotaka
[Person:1181389] Ladanyi, M
[Person:2318756] Holland, Eric C
created[InstanceEdit:9673549] Rothfels, Karen, 2020-01-08
journalGenes Dev.
pages2205-18
pubMedIdentifier20889717
titlePDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas
volume24
year2010
(literatureReference)[Pathway:9671555] Signaling by PDGFR in disease [Homo sapiens]
[Reaction:9672158] GRB2:SOS1 complex binds to PDGFRA extracellular domain dimers [Homo sapiens]
[Reaction:9672162] PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of PDGFRA extracellular domain dimers [Homo sapiens]
[Reaction:9672163] SOS-mediated nucleotide exchange on RAS downstream of PDGFRA extracellular domain dimers [Homo sapiens]
[Reaction:9672173] Autophosphorylation of PDGFRA extracellular domain dimers [Homo sapiens]
[Reaction:9672174] Ligand-independent dimerization of PDGFRA extracellular domain mutants [Homo sapiens]
[Reaction:9672178] PI3-kinase binds to PDGFRA extracellular domain dimers [Homo sapiens]
[Reaction:9673757] Ligand-independent dimerization of cytosolic PDGFRA and PDGFRB fusion proteins [Homo sapiens]
[Reaction:9673760] Ligand-independent dimerization of membrane-tethered fusions of PDGFRA or PDGFRB [Homo sapiens]
[Reaction:9673761] Autophosphorylation of membrane-tethered fusions of PDGFRA or PDGFRB [Homo sapiens]
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