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Details on Person PM20D1 hydrolyzes oleoyl-phe

Class:IdReaction:9673054
_displayNamePM20D1 hydrolyzes oleoyl-phe
_doReleaseTRUE
_timestamp2025-06-02 14:56:46
authored[InstanceEdit:9673162] D'Eustachio, Peter, 2020-01-06
catalystActivity[CatalystActivity:9673055] hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides of PM20D1 [extracellular region]
catalystActivityReference[CatalystActivityReference:9673051] hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides of PM20D1 [extracellular region] The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria
compartment[Compartment:984] extracellular region
created[InstanceEdit:9673046] D'Eustachio, Peter, 2020-01-05
crossReference[DatabaseIdentifier:9864455] RHEA:64129
edited[InstanceEdit:9673162] D'Eustachio, Peter, 2020-01-06
goBiologicalProcess[GO_BiologicalProcess:6808273] adaptive thermogenesis
input[SimpleEntity:109276] H2O [extracellular region]
[SimpleEntity:9673044] oleoyl-Phe [extracellular region]
internalReviewed[InstanceEdit:9946999] D'Eustachio, Peter, 2025-04-29
isChimericFALSE
literatureReference[LiteratureReference:9673058] The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria
modified[InstanceEdit:9673157] D'Eustachio, Peter, 2020-01-06
[InstanceEdit:9673818] D'Eustachio, Peter, 2020-01-09
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9864499] Stephan, Ralf, 2024-03-07
[InstanceEdit:9908912] Stephan, Ralf, 2024-04-24
[InstanceEdit:9946988] D'Eustachio, Peter, 2025-04-29
[InstanceEdit:9946998] D'Eustachio, Peter, 2025-04-29
[InstanceEdit:9953426] D'Eustachio, Peter, 2025-06-02
namePM20D1 hydrolyzes oleoyl-phe
negativePrecedingEvent[NegativePrecedingEvent:9908923] Futile Cycle: PM20D1 transforms oleoyl-phe from oleate and phe
output[SimpleEntity:351993] L-Phe [extracellular region]
[SimpleEntity:400431] OLEA [extracellular region]
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2020-03-17
reverseReaction
reviewed[InstanceEdit:9673817] Jassal, Bijay, May, Bruce, 2020-01-09
[InstanceEdit:9953425] Hill, David P, 2025-06-02
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9673064] R-HSA-9673054.4
structureModified[InstanceEdit:9946988] D'Eustachio, Peter, 2025-04-29
summation[Summation:9673159] Extracellular PM20D1 (N-fatty-acyl-amino acid synthase/hydro...
(hasEvent)[Pathway:9673163] Oleoyl-phe metabolism [Homo sapiens]
(precedingEvent)[NegativePrecedingEvent:9908909] Futile Cycle: PM20D1 hydrolyzes oleoyl-phe
(reverseReaction)[Reaction:9673053] PM20D1 transforms oleoyl-phe from oleate and phe [Homo sapiens]
(updatedInstance)[_UpdateTracker:9953639] Update Tracker - [Reaction:9673054] PM20D1 hydrolyzes oleoyl-phe - v93:[add_removeOutput]
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No pathways have been reviewed or authored by PM20D1 hydrolyzes oleoyl-phe (9673054)
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