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Query author contributions in Reactome

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Details on Person imatinib-sensitive PDGFR mutants [plasma membrane]

Class:IdDefinedSet:9672129
_displayNameimatinib-sensitive PDGFR mutants [plasma membrane]
_timestamp2020-01-13 03:55:09
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9672127] Rothfels, Karen, 2019-12-23
disease[Disease:1500689] cancer
hasMember
literatureReference[LiteratureReference:9671319] A precision therapy against cancers driven by KIT/PDGFRA mutations
[LiteratureReference:9674274] Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants
[LiteratureReference:9671911] PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib
[LiteratureReference:9671429] Sorafenib inhibits many kinase mutations associated with drug-resistant gastrointestinal stromal tumors
[LiteratureReference:9673492] A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome
[LiteratureReference:9671886] Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies
modified[InstanceEdit:9674382] Rothfels, Karen, 2020-01-13
nameimatinib-sensitive PDGFR mutants
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9672142] R-HSA-9672129.1
(hasMember)[DefinedSet:9674351] type II TKI sensitive PDGFR mutants [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by imatinib-sensitive PDGFR mutants [plasma membrane] (9672129)
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