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Details on Person Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies
| Class:Id | LiteratureReference:9671362 |
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| _displayName | Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies |
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| _timestamp | 2019-12-19 18:11:23 |
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| author | [Person:9671360] Schittenhelm, Marcus M
[Person:9671356] Shiraga, Sharon
[Person:9671357] Schroeder, Arin
[Person:9671361] Corbin, Amie S
[Person:9669218] Griffith, Diana
[Person:9656481] Lee, Francis Y
[Person:9671358] Bokemeyer, Carsten
[Person:9671359] Deininger, Michael W N
[Person:2053979] Druker, BJ
[Person:9669096] Heinrich, Michael C |
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| created | [InstanceEdit:9671363] Rothfels, Karen, 2019-12-19 |
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| journal | Cancer Res. |
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| pages | 473-81 |
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| pubMedIdentifier | 16397263 |
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| title | Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies |
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| volume | 66 |
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| year | 2006 |
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| (literatureReference) | [FailedReaction:9669855] Dasatinib-resistant KIT mutants do not bind dasatinib [Homo sapiens]
[Pathway:9669914] Dasatinib-resistant KIT mutants [Homo sapiens]
[Reaction:9670414] KIT mutants bind SFKs [Homo sapiens] |
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