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Details on Person Bajaj, S P

Class:Id	Person:9670899
_displayName	Bajaj, S P
_timestamp	2019-12-17 05:24:33
created	[InstanceEdit:9670828] Shamovsky, Veronica, 2019-12-17
firstname	S P
initial	SP
surname	Bajaj
(author)	[LiteratureReference:9670818] Characterization of three abnormal factor IX variants (Bm Lake Elsinore, Long Beach, and Los Angeles) of hemophilia-B. Evidence for defects affecting the latent catalytic site [LiteratureReference:9670825] Replacement of isoleucine-397 by threonine in the clotting proteinase factor IXa (Los Angeles and Long Beach variants) affects macromolecular catalysis but not L-tosylarginine methyl ester hydrolysis. Lack of correlation between the ox brain prothrombin time and the mutation site in the variant proteins [LiteratureReference:9670843] Molecular defect in factor IXBm Lake Elsinore. Substitution of Ala390 by Val in the catalytic domain [LiteratureReference:9671002] Hemophilia B caused by five different nondeletion mutations in the protease domain of factor IX [LiteratureReference:9671011] Experimental and theoretical evidence supporting the role of Gly363 in blood coagulation factor IXa (Gly193 in chymotrypsin) for proper activation of the proenzyme [LiteratureReference:9671036] High affinity Ca(2+)-binding site in the serine protease domain of human factor VIIa and its role in tissue factor binding and development of catalytic activity [LiteratureReference:9671732] Activation of human factor VII in the initiation of tissue factor-dependent coagulation [LiteratureReference:9673271] Analysis of the factor XI variant Arg184Gly suggests a structural basis for factor IX binding to factor XIa [LiteratureReference:9929057] The first epidermal growth factor-like domains of factor Xa and factor IXa are important for the activation of the factor VII--tissue factor complex [LiteratureReference:9934452] Factor IXa:factor VIIIa interaction. helix 330-338 of factor ixa interacts with residues 558-565 and spatially adjacent regions of the a2 subunit of factor VIIIa
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No pathways have been reviewed or authored by Bajaj, S P (9670899)