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Details on Person FIX is secreted

Class:IdBlackBoxEvent:9670673
_displayNameFIX is secreted
_doReleaseTRUE
_timestamp2020-05-26 22:03:32
authored[InstanceEdit:9670650] Shamovsky, Veronica, 2019-12-12
compartment[Compartment:17957] endoplasmic reticulum lumen
[Compartment:984] extracellular region
created[InstanceEdit:9670669] Shamovsky, Veronica, 2019-12-12
edited[InstanceEdit:9690131] Shamovsky, Veronica, 2020-05-26
input[EntityWithAccessionedSequence:9631373] F9(29-461) [endoplasmic reticulum lumen] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9670652] Biology of factor IX
[LiteratureReference:9670687] Expression, purification, and characterization of recombinant gamma-carboxylated factor IX synthesized in Chinese hamster ovary cells
modified[InstanceEdit:9676086] Shamovsky, Veronica, 2020-02-07
[InstanceEdit:9676353] Shamovsky, Veronica, 2020-02-13
[InstanceEdit:9681504] Shamovsky, Veronica, 2020-04-02
[InstanceEdit:9686299] Shamovsky, Veronica, 2020-04-29
[InstanceEdit:9687144] Shamovsky, Veronica, 2020-05-06
[InstanceEdit:9690135] Shamovsky, Veronica, 2020-05-26
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameFIX is secreted
output[EntityWithAccessionedSequence:140886] 12xCbxE-3D-F9(47-461) [extracellular region] [Homo sapiens]
releaseDate2020-06-10
reviewed[InstanceEdit:9673821] D'Eustachio, Peter, 2020-01-09
[InstanceEdit:9681505] Zhang, Bin, 2020-04-02
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9670707] R-HSA-9670673.2
summation[Summation:9670658] Coagulation Factor IX (FIX) is synthesized by hepatocytes (Y...
(hasEvent)[Pathway:140837] OBSOLETE_Intrinsic Pathway of Fibrin Clot Formation_REPLACEMENT_9769743_9970672 [Homo sapiens]
[Pathway:9769743] Amplification and propagation of coagulation cascade [Homo sapiens]
(normalReaction)[FailedReaction:9670888] F9 variant is not secreted [Homo sapiens]
(precedingEvent)[Reaction:158333] factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) [Homo sapiens]
[Reaction:9929051] TF:FVIIa+FIX -> TF:FVIIa:FIXa + FIX activation peptide (TF:F7a catalyst) [Homo sapiens]
[Reaction:9936467] factor IX -> factor IXa + factor IX activation peptide (kallikrein catalyst) [Homo sapiens]
(updatedInstance)[_UpdateTracker:9939796] Update Tracker - [BlackBoxEvent:9670673] FIX is secreted - v92:[modifyText]
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No pathways have been reviewed or authored by FIX is secreted (9670673)