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Details on Person Oncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus in gastrointestinal stromal tumors

Class:IdLiteratureReference:9670495
_displayNameOncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus in gastrointestinal stromal tumors
_timestamp2019-12-09 21:59:11
author[Person:9670494] Obata, Y
[Person:5690679] Horikawa, K
[Person:5320035] Takahashi, T
[Person:9670492] Akieda, Y
[Person:6788438] Tsujimoto, M
[Person:6801906] Fletcher, J A
[Person:9670490] Esumi, H
[Person:2997719] Nishida, T
[Person:9670493] Abe, R
created[InstanceEdit:9670491] Rothfels, Karen, 2019-12-09
journalOncogene
pages3661-3672
pubMedIdentifier28192400
titleOncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus in gastrointestinal stromal tumors
volume36
year2017
(literatureReference)[BlackBoxEvent:9670412] Phosphorylation of STATs downstream of KIT mutants [Homo sapiens]
[Reaction:9670413] JAK2 binds to p-KIT mutants [Homo sapiens]
[Reaction:9670416] Recruitment of STATs by KIT mutants [Homo sapiens]
[Reaction:9670417] Dimerization of STATs downstream of KIT mutants [Homo sapiens]
[Reaction:9670426] Disassociation and translocation of STATs to the nucleus downstream of KIT mutants [Homo sapiens]
[Reaction:9670428] KIT mutants bind GRB2-SOS [Homo sapiens]
[Reaction:9670431] Phosphorylated KIT mutants bind PI3K [Homo sapiens]
[Reaction:9670436] p-KIT mutants:GRB2:SOS catalyzes nucleotide exchange on RAS [Homo sapiens]
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