Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
| Class:Id | EntityFunctionalStatus:9670400 |
|---|---|
| _displayName | gain_of_function of p-KIT mutants:GRB2:SOS [plasma membrane] |
| _timestamp | 2019-12-09 15:36:20 |
| created | [InstanceEdit:9670401] Rothfels, Karen, 2019-12-09 |
| diseaseEntity | [Complex:9670365] p-KIT mutants:GRB2:SOS [plasma membrane] [Homo sapiens] |
| functionalStatus | [FunctionalStatus:2632527] gain_of_function via inframe_deletion [FunctionalStatus:2362351] gain_of_function via non_conservative_missense_variant |
| normalEntity | [Complex:205202] GRB2:SOS1:p-KIT complex [plasma membrane] [Homo sapiens] |
| (entityFunctionalStatus) | [Reaction:9670436] p-KIT mutants:GRB2:SOS catalyzes nucleotide exchange on RAS [Homo sapiens] |
| [Change default viewing format] | |