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Details on Person Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours
| Class:Id | LiteratureReference:9669094 |
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| _displayName | Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours |
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| _timestamp | 2019-12-02 20:53:45 |
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| author | [Person:9669090] Serrano, César
[Person:9669080] Mariño-Enríquez, Adrián
[Person:9669085] Tao, Derrick L
[Person:9669097] Ketzer, Julia
[Person:9669082] Eilers, Grant
[Person:9669092] Zhu, Meijun
[Person:9669091] Yu, Channing
[Person:9669089] Mannan, Aristotle M
[Person:9669086] Rubin, Brian P
[Person:9669081] Demetri, George D
[Person:9669095] Raut, Chandrajit P
[Person:9669093] Presnell, Ajia
[Person:9669079] McKinley, Arin
[Person:9669096] Heinrich, Michael C
[Person:9669078] Czaplinski, Jeffrey T
[Person:9669084] Sicinska, Ewa
[Person:9669098] Bauer, Sebastian
[Person:9669088] George, Suzanne
[Person:9669087] Fletcher, Jonathan A |
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| created | [InstanceEdit:9669083] Rothfels, Karen, 2019-12-02 |
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| journal | Br. J. Cancer |
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| pages | 612-620 |
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| pubMedIdentifier | 30792533 |
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| title | Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours |
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| volume | 120 |
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| year | 2019 |
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| (literatureReference) | [DefinedSet:9669742] dovitinib sensitive KIT mutants [plasma membrane] [Homo sapiens]
[DefinedSet:9669750] imatinib sensitive KIT mutants [plasma membrane] [Homo sapiens]
[DefinedSet:9669772] nilotinib resistant KIT mutants [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9670336] KIT V560_L576del [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9670343] KIT W557_K558del [plasma membrane] [Homo sapiens]
[RegulationReference:9669883] Negative regulation by 'KIT:sSCF dimer:KIT:type I KIT binding TKIs: [plasma membrane]' Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours
[FailedReaction:9669855] Dasatinib-resistant KIT mutants do not bind dasatinib [Homo sapiens]
[FailedReaction:9669859] Imatinib-resistant KIT mutants do not bind imatinib [Homo sapiens]
[FailedReaction:9669863] Masitinib-resistant KIT mutants do not bind masitinib [Homo sapiens]
[FailedReaction:9669868] Nilotinib-resistant KIT mutants do not bind nilotinib [Homo sapiens] |
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