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Details on Person CHMP7 binds LEMD2

Class:IdReaction:9668335
_displayNameCHMP7 binds LEMD2
_doReleaseTRUE
_timestamp2022-02-08 22:12:57
authored[InstanceEdit:9667932] Gerace, Larry, 2019-11-07
compartment[Compartment:70101] cytosol
[Compartment:13231] nuclear envelope
created[InstanceEdit:9668337] Orlic-Milacic, Marija, 2019-11-25
edited[InstanceEdit:9668537] Orlic-Milacic, Marija, 2019-11-26
input[EntityWithAccessionedSequence:3067329] LEMD2 [nuclear envelope] [Homo sapiens]
[EntityWithAccessionedSequence:917703] CHMP7 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9668327] LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells
modified[InstanceEdit:9668515] Orlic-Milacic, Marija, 2019-11-26
[InstanceEdit:9668545] Orlic-Milacic, Marija, 2019-11-27
[InstanceEdit:9668551] Orlic-Milacic, Marija, 2019-11-27
[InstanceEdit:9676327] Orlic-Milacic, Marija, 2020-02-12
[InstanceEdit:9676686] Orlic-Milacic, Marija, 2020-02-19
[InstanceEdit:9764075] Orlic-Milacic, Marija, 2022-02-08
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCHMP7 binds LEMD2
negativePrecedingEvent[NegativePrecedingEvent:9764073] Futile Cycle: VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope
output[Complex:9668512] LEMD2:CHMP7 [nuclear envelope] [Homo sapiens]
releaseDate2020-03-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9668346] R-HSA-9668335.3
summation[Summation:9668342] The ESCRT-III subunit CHMP7 binds LEMD2 (LEM2) at holes in t...
(hasEvent)[Pathway:9668328] Sealing of the nuclear envelope (NE) by ESCRT-III [Homo sapiens]
(precedingEvent)[Reaction:9668398] CHMP7 binds CHMP4B, which recruits other subunits of the ESCRT-III complex [Homo sapiens]
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No pathways have been reviewed or authored by CHMP7 binds LEMD2 (9668335)