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Details on Person ALK binds ligand midkine (MDK)

Class:IdReaction:9667914
_displayNameALK binds ligand midkine (MDK)
_doReleaseTRUE
_timestamp2021-05-17 14:43:16
authored[InstanceEdit:9667919] Orlic-Milacic, Marija, 2019-11-18
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:9667901] Orlic-Milacic, Marija, 2019-11-18
edited[InstanceEdit:9667919] Orlic-Milacic, Marija, 2019-11-18
input[EntityWithAccessionedSequence:201502] ALK [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:2160953] MDK [extracellular region] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9667900] Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types
modified[InstanceEdit:9729590] Rothfels, Karen, 2021-04-30
[InstanceEdit:9729893] Rothfels, Karen, 2021-05-04
[InstanceEdit:9731211] Rothfels, Karen, 2021-05-17
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameALK binds ligand midkine (MDK)
output[Complex:9667909] MDK:ALK [plasma membrane] [Homo sapiens]
releaseDate2021-06-09
reviewed[InstanceEdit:9729891] Inghirami, Giorgio, 2021-05-04
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9667917] R-HSA-9667914.2
summation[Summation:9667903] ALK receptor tyrosine kinase binds to secreted growth factor...
(hasEvent)[Pathway:9851151] MDK and PTN in ALK signaling [Homo sapiens]
(precedingEvent)[Reaction:9700137] ALK:MDK dimerization [Homo sapiens]
[Reaction:9700662] Liganded-ALK dimer binds type I ALK-binding TKIs [Homo sapiens]
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No pathways have been reviewed or authored by ALK binds ligand midkine (MDK) (9667914)