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Details on Person Chrna9:Chrna10:AcCho transports calcium ions from the extracellular region to the cytosol

Class:Id	Reaction:9667850
_displayName	Chrna9:Chrna10:AcCho transports calcium ions from the extracellular region to the cytosol
_doRelease	TRUE
_timestamp	2020-12-12 09:57:46
authored	[InstanceEdit:9667832] May, Bruce, 2019-11-17
catalystActivity	[CatalystActivity:9667859] calcium channel activity of Chrna9:Chrna10:AcCho [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9667852] May, Bruce, 2019-11-18
edited	[InstanceEdit:9667832] May, Bruce, 2019-11-17
input	[SimpleEntity:74112] Ca2+ [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:9667833] Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells [LiteratureReference:9667846] alpha10: a determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells [LiteratureReference:9667851] Mixed nicotinic-muscarinic properties of the alpha9 nicotinic cholinergic receptor [LiteratureReference:9667839] The alpha9alpha10 nicotinic acetylcholine receptor is permeable to and is modulated by divalent cations [LiteratureReference:9667834] Biophysical and pharmacological characterization of nicotinic cholinergic receptors in rat cochlear inner hair cells
modified	[InstanceEdit:9699208] May, Bruce, 2020-09-14 [InstanceEdit:9706573] May, Bruce, 2020-11-07 [InstanceEdit:9709306] May, Bruce, 2020-12-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Chrna9:Chrna10:AcCho transports calcium ions from the extracellular region to the cytosol
output	[SimpleEntity:74016] Ca2+ [cytosol]
releaseDate	2021-03-23
reviewed	[InstanceEdit:9699206] Furness, David N, 2020-09-14 [InstanceEdit:9699205] Dallos, Peter, 2020-09-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48895] Rattus norvegicus
stableIdentifier	[StableIdentifier:9667862] R-RNO-9667850.2
summation	[Summation:9667838] In response to binding acetylcholine (AcCho), the Chrna9:Chr...
(inferredFrom)	[Reaction:9663785] CHRNA9:CHRNA10:AcCho transports Ca2+ from the extracellular region to the cytosol [Homo sapiens]
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