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Details on Person In response to binding acetylcholine (AcCho), the CHRNA9:CHR...
| Class:Id | Summation:9667847 |
|---|---|
| _displayName | In response to binding acetylcholine (AcCho), the CHRNA9:CHR... |
| _timestamp | 2020-07-29 13:33:43 |
| created | [InstanceEdit:9667852] May, Bruce, 2019-11-18 |
| modified | [InstanceEdit:9667870] May, Bruce, 2019-11-18 [InstanceEdit:9668878] May, Bruce, 2019-11-30 [InstanceEdit:9670005] May, Bruce, 2019-12-03 [InstanceEdit:9696798] May, Bruce, 2020-07-29 |
| text | In response to binding acetylcholine (AcCho), the CHRNA9:CHRNA10 receptor transports calcium ions from the extracellular region to the cytosol (inferred from rat homologs). CHRNA9:CHRNA10 receptors are clustered at cholinergic synapses in the basal region of outer hair cells (OHCs) (inferred from rat homologs). The influx of calcium causes opening of SK2 channels (KCNN2) and BK channels (KCNMA1:KCNMB1), efflux of potassium ions, hyperpolarization, and inhibition of contraction of the OHCs. |
| (summation) | [Reaction:9663785] CHRNA9:CHRNA10:AcCho transports Ca2+ from the extracellular region to the cytosol [Homo sapiens] |
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No pathways have been reviewed or authored by In response to binding acetylcholine (AcCho), the CHRNA9:CHR... (9667847)
