Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person F8 A20_M2143delinsMRIQDPGK [endoplasmic reticulum lumen]

Class:IdEntityWithAccessionedSequence:9666368
_displayNameF8 A20_M2143delinsMRIQDPGK [endoplasmic reticulum lumen]
_timestamp2019-12-27 09:12:34
compartment[Compartment:17957] endoplasmic reticulum lumen
created[InstanceEdit:9666357] Shamovsky, Veronica, 2019-11-05
crossReference[DatabaseIdentifier:9672535] ClinVar:RCV000010863
disease[Disease:9661959] factor VIII deficiency
endCoordinate2351
hasModifiedResidue[FragmentReplacedModification:9666343] Replacement of residues 20 to 2143 by MRIQDPGK
literatureReference[LiteratureReference:9666369] Endogenous factor VIII synthesis from the intron 22-inverted F8 locus may modulate the immunogenicity of replacement therapy for hemophilia A
[LiteratureReference:9666359] The intron-22-inverted F8 locus permits factor VIII synthesis: explanation for low inhibitor risk and a role for pharmacogenomics
modified[InstanceEdit:9672533] Shamovsky, Veronica, 2019-12-27
nameF8 A20_M2143delinsMRIQDPGK
FVIII A20_M2143delinsMRIQDPGK
referenceEntity[ReferenceGeneProduct:54602] UniProt:P00451 F8 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9666376] R-HSA-9666368.1
startCoordinate20
(hasMember)[CandidateSet:9661970] Non-secretable F8 variant [endoplasmic reticulum lumen] [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by F8 A20_M2143delinsMRIQDPGK [endoplasmic reticulum lumen] (9666368)
Follow Reactome