Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations

Class:IdLiteratureReference:9666001
_displayNameActionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations
_timestamp2019-11-01 03:23:12
author[Person:9666006] Pahuja, Kanika Bajaj
[Person:9665995] Nguyen, Thong T
[Person:2399670] Jaiswal, Bijay S
[Person:9666010] Prabhash, Kumar
[Person:9666021] Thaker, Tarjani M
[Person:8959656] Senger, Kate
[Person:2399700] Chaudhuri, Subhra
[Person:2399714] Kljavin, Noelyn M
[Person:9666002] Antony, Aju
[Person:5218951] Phalke, Sameer
[Person:9666013] Kumar, Prasanna
[Person:9666030] Mravic, Marco
[Person:9666029] Stawiski, Eric W
[Person:9665996] Vargas, Derek
[Person:9666024] Durinck, Steffen
[Person:9666008] Gupta, Ravi
[Person:3232117] Khanna-Gupta, Arati
[Person:9666017] Trabucco, Sally E
[Person:9666018] Sokol, Ethan S
[Person:9666025] Hartmaier, Ryan J
[Person:9666007] Singh, Ashish
[Person:9666004] Chougule, Anuradha
[Person:9666012] Trivedi, Vaishakhi
[Person:1614687] Dutt, A
[Person:9666016] Patil, Vijay
[Person:9666022] Joshi, Amit
[Person:9666026] Noronha, Vanita
[Person:9666015] Ziai, James
[Person:9666014] Banavali, Sripad D
[Person:9665992] Ramprasad, Vedam
[Person:9665994] DeGrado, William F
[Person:9666005] Bueno, Raphael
[Person:9666028] Jura, Natalia
[Person:2399668] Seshagiri, Somasekar
created[InstanceEdit:9665998] Orlic-Milacic, Marija, 2019-11-01
journalCancer Cell
pages792-806.e5
pubMedIdentifier30449325
titleActionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations
volume34
year2018
(literatureReference)[Pathway:1227990] Signaling by ERBB2 in Cancer [Homo sapiens]
[Pathway:9665686] Signaling by ERBB2 TMD/JMD mutants [Homo sapiens]
[Reaction:9665696] ERBB2 TMD/JMD mutants bind trastuzumab [Homo sapiens]
[Reaction:9665697] ERBB2 TMD/JMD mutants hetrodimerize [Homo sapiens]
[Reaction:9665702] ERBB2 TMD/JMD mutants bind TKIs [Homo sapiens]
[Reaction:9665703] ERBB2 TMD/JMD mutants bind pertuzumab [Homo sapiens]
[FailedReaction:9665708] ERBB2 TMD/JMD mutants do not bind pertuzumab [Homo sapiens]
[Reaction:9665709] ERBB2 TMD/JMD heterodimers trans-autophosphorylate [Homo sapiens]
[Pathway:9665737] Drug resistance in ERBB2 TMD/JMD mutants [Homo sapiens]
[EntityWithAccessionedSequence:9665752] ERBB2 V659E [plasma membrane] [Homo sapiens]
List all 23 refering instances
[Change default viewing format]
No pathways have been reviewed or authored by Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations (9666001)
Follow Reactome