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Query author contributions in Reactome

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Details on Person gain_of_function of p-6Y-ERBB2 TMD/JMD mutants (RAS):EGF:p-6Y-EGFR [plasma membrane]

Class:IdEntityFunctionalStatus:9665918
_displayNamegain_of_function of p-6Y-ERBB2 TMD/JMD mutants (RAS):EGF:p-6Y-EGFR [plasma membrane]
_timestamp2019-11-01 02:17:06
created[InstanceEdit:9665919] Orlic-Milacic, Marija, 2019-11-01
diseaseEntity[Complex:9665917] p-6Y-ERBB2 TMD/JMD mutants (RAS):EGF:p-6Y-EGFR [plasma membrane] [Homo sapiens]
functionalStatus[FunctionalStatus:2362351] gain_of_function via non_conservative_missense_variant
normalEntity[CandidateSet:1963587] Phosphorylated ERBB2:EGFR heterodimers [plasma membrane] [Homo sapiens]
(entityFunctionalStatus)[Reaction:9665698] Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR bind GRB2:SOS1 [Homo sapiens]
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No pathways have been reviewed or authored by gain_of_function of p-6Y-ERBB2 TMD/JMD mutants (RAS):EGF:p-6Y-EGFR [plasma membrane] (9665918)