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Details on Person Surface-exposed hemophilic mutations across the factor VIII C2 domain have variable effects on stability and binding activities

Class:Id	LiteratureReference:9665821
_displayName	Surface-exposed hemophilic mutations across the factor VIII C2 domain have variable effects on stability and binding activities
_timestamp	2019-11-01 01:32:16
author	[Person:9665801] Spiegel, P Clint [Person:9665835] Murphy, Paul [Person:500143] Stoddard, Barry L
created	[InstanceEdit:9665826] Shamovsky, Veronica, 2019-11-01
journal	J. Biol. Chem.
pages	53691-8
pubMedIdentifier	15471879
title	Surface-exposed hemophilic mutations across the factor VIII C2 domain have variable effects on stability and binding activities
volume	279
year	2004
(literatureReference)	[EntityWithAccessionedSequence:9665786] F8 R2323H [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:9665804] F8 P2319L [extracellular region] [Homo sapiens] [CandidateSet:9665831] FVIII C1, C2 domain variants [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:9665836] F8 P2319S [extracellular region] [Homo sapiens] [Complex:9670192] FVIIIa variants [extracellular region] [Homo sapiens] [DefinedSet:9670218] F8 A3-C1-C2 variants defective in phospholipid binding. [extracellular region] [Homo sapiens] [FailedReaction:9665809] F8 variant does not bind von Willebrand factor [Homo sapiens] [FailedReaction:9670189] F8 variant does not bind the cell membrane [Homo sapiens] [Pathway:9672393] Defective F8 binding to von Willebrand factor [Homo sapiens] [Pathway:9672395] Defective F8 binding to the cell membrane [Homo sapiens] List all 12 refering instances
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