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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person F8 A2220del [extracellular region]

Class:IdEntityWithAccessionedSequence:9665793
_displayNameF8 A2220del [extracellular region]
_timestamp2019-11-01 01:32:46
compartment[Compartment:984] extracellular region
created[InstanceEdit:9665826] Shamovsky, Veronica, 2019-11-01
disease[Disease:9661959] factor VIII deficiency
endCoordinate2351
hasModifiedResidue[FragmentDeletionModification:9665841] Deletion of residues 2220 to 2220
literatureReference[LiteratureReference:9665814] Storage of factor VIII variants with impaired von Willebrand factor binding in Weibel-Palade bodies in endothelial cells
[LiteratureReference:9665800] Deletion of alanine 2201 in the FVIII C2 domain results in mild hemophilia A by impairing FVIII binding to VWF and phospholipids and destroys a major FVIII antigenic determinant involved in inhibitor development
nameF8 A2220del
FVIII A2220del
referenceEntity[ReferenceGeneProduct:54602] UniProt:P00451 F8 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9665845] R-HSA-9665793.1
startCoordinate1668
(hasMember)[CandidateSet:9665831] FVIII C1, C2 domain variants [extracellular region] [Homo sapiens]
[DefinedSet:9670218] F8 A3-C1-C2 variants defective in phospholipid binding. [extracellular region] [Homo sapiens]
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No pathways have been reviewed or authored by F8 A2220del [extracellular region] (9665793)
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