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Details on Person ERBB2 V659E [plasma membrane]

Class:IdEntityWithAccessionedSequence:9665752
_displayNameERBB2 V659E [plasma membrane]
_timestamp2019-11-08 14:38:24
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9665760] Orlic-Milacic, Marija, 2019-11-01
crossReference[DatabaseIdentifier:9667215] COSMIC:COSV54062460
[DatabaseIdentifier:9667216] COSMIC:COSV54065138
disease[Disease:1500689] cancer
[Disease:2327989] bile duct carcinoma
[Disease:8853117] lung adenocarcinoma
[Disease:1247848] non-small cell lung carcinoma
endCoordinate1255
hasModifiedResidue[ReplacedResidue:9665762] L-valine 659 replaced with L-glutamic acid
literatureReference[LiteratureReference:9666001] Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations
modified[InstanceEdit:9667217] Orlic-Milacic, Marija, 2019-11-08
nameERBB2 V659E
referenceEntity[ReferenceGeneProduct:54422] UniProt:P04626 ERBB2 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9665774] R-HSA-9665752.1
startCoordinate23
(hasCandidate)[CandidateSet:9665885] ERBB2 TMD/JMD mutants [plasma membrane] [Homo sapiens]
(hasMember)[DefinedSet:9665934] ERBB2 TMD/JMD mutants (neratinib) [plasma membrane] [Homo sapiens]
[DefinedSet:9665955] ERBB2 TMD/JMD mutants (trastuzumab) [plasma membrane] [Homo sapiens]
[DefinedSet:9665964] ERBB2 TMD/JMD mutants (pertuzumab resistant) [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by ERBB2 V659E [plasma membrane] (9665752)