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Details on Person ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5

Class:Id	Reaction:9664888
_displayName	ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5
_doRelease	TRUE
_timestamp	2022-02-14 17:55:46
authored	[InstanceEdit:9665107] Varusai, Thawfeek, 2019-10-29
compartment	[Compartment:17947] peroxisomal membrane
created	[InstanceEdit:9664866] Varusai, Thawfeek, 2019-10-28
edited	[InstanceEdit:9674460] Varusai, Thawfeek, 2020-01-13
input	[Complex:9665178] ATM dimer:p-PEX5 [peroxisomal membrane] [Homo sapiens] [DefinedSet:113595] Ub [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8963776] ATM functions at the peroxisome to induce pexophagy in response to ROS
modified	[InstanceEdit:9664912] Varusai, Thawfeek, 2019-10-28 [InstanceEdit:9665186] Varusai, Thawfeek, 2019-10-30 [InstanceEdit:9672550] Varusai, Thawfeek, 2020-01-02 [InstanceEdit:9673101] Varusai, Thawfeek, 2020-01-06 [InstanceEdit:9674460] Varusai, Thawfeek, 2020-01-13 [InstanceEdit:9677120] Matthews, Lisa, 2020-02-27 [InstanceEdit:9681506] Varusai, Thawfeek, 2020-04-02 [InstanceEdit:9682019] Varusai, Thawfeek, 2020-04-07 [InstanceEdit:9765010] May, Bruce, 2022-02-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5
output	[Complex:9665179] ATM dimer:Ub-p-PEX5 [peroxisomal membrane] [Homo sapiens]
precedingEvent	[Reaction:9664862] ATM dimer:PEX5 phosphorylates PEX5 [Homo sapiens] [Reaction:9664879] ATM:PEX5 binds ATM [Homo sapiens] [Reaction:9674127] USP30 deubiquitinates ATM dimer:Ub-p-PEX5 [Homo sapiens] [Reaction:9674131] USP30 binds ATM dimer:Ub-p-PEX5 [Homo sapiens]
releaseDate	2020-03-17
reviewed	[InstanceEdit:9682017] Metzakopian, Emmanouil, 2019-10-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9664896] R-HSA-9664888.4
summation	[Summation:9664848] Phosphorylation of Peroxisomal targeting signal 1 receptor p...
(hasEvent)	[Pathway:9664873] Pexophagy [Homo sapiens]
(precedingEvent)	[Reaction:9664892] SQSTM1 binds ATM dimer:Ub-p-PEX5 [Homo sapiens] [Reaction:9674131] USP30 binds ATM dimer:Ub-p-PEX5 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9775221] Update Tracker - [Reaction:9664888] ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 - v80:[addInput]
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No pathways have been reviewed or authored by ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (9664888)