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Details on Person Opsonized leishmania amastigote binds FCGR3

Class:Id	Reaction:9664268
_displayName	Opsonized leishmania amastigote binds FCGR3
_doRelease	TRUE
_timestamp	2020-02-25 18:24:26
authored	[InstanceEdit:9673434] Murillo, Julieth, 2020-01-07 [InstanceEdit:9673371] Jassal, Bijay, 2020-01-07
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9664264] Murillo, Julieth, 2019-10-22
disease	[Disease:9674660] cutaneous leishmaniasis
edited	[InstanceEdit:9673434] Murillo, Julieth, 2020-01-07 [InstanceEdit:9673371] Jassal, Bijay, 2020-01-07
input	[Complex:2029097] FCGRIIIA:CD3G/CD3Z dimers [plasma membrane] [Homo sapiens] [DefinedSet:9666422] IgG:Lma antigens [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9664284] FcgammaRIII mediates immunoglobulin G-induced interleukin-10 and is required for chronic Leishmania mexicana lesions [LiteratureReference:9664259] IgG1 is pathogenic in Leishmania mexicana infection [LiteratureReference:9664276] Leishmania mexicana infection induces IgG to parasite surface glycoinositol phospholipids that can induce IL-10 in mice and humans
modified	[InstanceEdit:9673430] Murillo, Julieth, 2020-01-07 [InstanceEdit:9673793] Murillo, Julieth, 2020-01-09 [InstanceEdit:9674661] Murillo, Julieth, 2020-01-22 [InstanceEdit:9675740] Murillo, Julieth, 2020-02-05 [InstanceEdit:9676364] Jassal, Bijay, 2020-02-13 [InstanceEdit:9676933] Jassal, Bijay, 2020-02-24 [InstanceEdit:9676966] Murillo, Julieth, 2020-02-24 [InstanceEdit:9677019] Murillo, Julieth, 2020-02-25 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Opsonized leishmania amastigote binds FCGR3
output	[Complex:9664263] IgG:Lma antigens:FCGR3A:CD3 dimers [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:9664285] IgG binds the surface of the amastigote form of Leishmania [Homo sapiens] [Reaction:9664397] IgG binds LPG1G2 in the amastigote form of Leishmania [Homo sapiens]
relatedSpecies	[Species:9658193] Leishmania major
releaseDate	2020-03-17
reviewed	[InstanceEdit:9675734] Gregory, David J, 2020-02-04
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9664287] R-HSA-9664268.2
summation	[Summation:9664279] Leishmania amastigotes parasites opsonized by IgG are more s...
(hasEvent)	[Pathway:9664323] FCGR3A-mediated IL10 synthesis [Homo sapiens]
(precedingEvent)	[Reaction:9664275] Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers [Homo sapiens]
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No pathways have been reviewed or authored by Opsonized leishmania amastigote binds FCGR3 (9664268)