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Details on Person Atp2b2 (wa isoform) located in the plasma membrane of stereo...
| Class:Id | Summation:9664215 |
|---|---|
| _displayName | Atp2b2 (wa isoform) located in the plasma membrane of stereo... |
| _timestamp | 2019-12-14 08:01:50 |
| created | [InstanceEdit:9664220] May, Bruce, 2019-10-22 |
| modified | [InstanceEdit:9664487] May, Bruce, 2019-10-23 [InstanceEdit:9667863] May, Bruce, 2019-11-18 [InstanceEdit:9668878] May, Bruce, 2019-11-30 [InstanceEdit:9670755] May, Bruce, 2019-12-14 |
| text | Atp2b2 (wa isoform) located in the plasma membrane of stereocilia bundles of inner hair cells and outer hair cells transports calcium ions from the cytosol to the extracellular region with concomitant hydrolysis of ATP (Dumont et al. 2001, Grati et al. 2006, Hill et al. 2006, Chen et al. 2012). Atp2b2 appears to facilitate an efflux of calcium ions that enter the stereocilia during depolarization caused by the opening of the mechanoelectrical transduction channel, hence Atp2b2 plays a role in repolarization of the cell (Beurg et al. 2010) |
| (summation) | [Reaction:9664232] Atp2b2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region [Rattus norvegicus] |
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No pathways have been reviewed or authored by Atp2b2 (wa isoform) located in the plasma membrane of stereo... (9664215)
