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Details on Person Kcnq4 located on the basal membrane of outer hair cells (OHC...
| Class:Id | Summation:9664163 |
|---|---|
| _displayName | Kcnq4 located on the basal membrane of outer hair cells (OHC... |
| _timestamp | 2019-12-03 07:25:39 |
| created | [InstanceEdit:9664104] May, Bruce, 2019-10-21 |
| modified | [InstanceEdit:9667832] May, Bruce, 2019-11-17 [InstanceEdit:9667863] May, Bruce, 2019-11-18 [InstanceEdit:9668878] May, Bruce, 2019-11-30 [InstanceEdit:9670005] May, Bruce, 2019-12-03 |
| text | Kcnq4 located on the basal membrane of outer hair cells (OHCs) (Kharkovets et al. 2000, Beisel et al. 2000, Kharkovets et al. 2006, Beisel et al. 2005, Winter et al. 2006) and inner hair cells (Kharkovets et al. 2000, Beisel et al. 2005) transports potassium ions along the concentration gradient from the cytosol to the extracellular region (Kharkovets et al. 2006). The resulting efflux of potassium is believed to be responsible for the I(K,n) current that plays a role in setting the resting potential of the cell and in repolarizing the cell (Oliver et al. 2003, Xu et al. 2007). Kcnq4 is located predominantlly in the basal membrane of OHCs (Kharkovets et al. 2000, Winter et al. 2006) and absence of Kcnq4 causes increased depolarization and degeneration of OHCs (Kharkovets et al. 2006). |
| (summation) | [Reaction:9659557] Kcnq4 transports K+ from the cytosol to the extracellular region [Mus musculus] |
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No pathways have been reviewed or authored by Kcnq4 located on the basal membrane of outer hair cells (OHC... (9664163)
