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Query author contributions in Reactome

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Details on Person OGG1 D268N [nucleoplasm]

Class:IdEntityWithAccessionedSequence:9663721
_displayNameOGG1 D268N [nucleoplasm]
_timestamp2019-10-16 11:24:59
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9663728] Orlic-Milacic, Marija, 2019-10-10
crossReference[DatabaseIdentifier:9663724] ClinGen:CA351714656
disease[Disease:9663832] genetic disease
endCoordinate345
hasModifiedResidue[ReplacedResidue:9663729] L-aspartic acid 268 replaced with L-asparagine
literatureReference[LiteratureReference:9663845] Reciprocal "flipping" underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase
[LiteratureReference:9663842] The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine
[LiteratureReference:9663840] Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase
modified[InstanceEdit:9663833] Orlic-Milacic, Marija, 2019-10-16
[InstanceEdit:9663849] Orlic-Milacic, Marija, 2019-10-16
nameOGG1 D268N
OGG1 Asp268Asn
referenceEntity[ReferenceGeneProduct:60888] UniProt:O15527 OGG1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9663730] R-HSA-9663721.1
startCoordinate1
(hasMember)[CandidateSet:9656300] OGG1 mutants (8oxoG hydrolysis) [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by OGG1 D268N [nucleoplasm] (9663721)
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