Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person The phosphorylation of disintegrin and metalloproteinase dom...
| Class:Id | Summation:9663421 |
|---|---|
| _displayName | The phosphorylation of disintegrin and metalloproteinase dom... |
| _timestamp | 2020-02-13 11:31:50 |
| created | [InstanceEdit:9663453] Murillo, Julieth, 2019-10-01 |
| literatureReference | [LiteratureReference:9663402] Polo-like kinase 2, a novel ADAM17 signaling component, regulates tumor necrosis factor α ectodomain shedding |
| modified | [InstanceEdit:9676361] Jassal, Bijay, 2020-02-13 [InstanceEdit:9676367] Jassal, Bijay, 2020-02-13 |
| text | The phosphorylation of disintegrin and metalloproteinase domain-containing protein 17 (ADAM17) by PLK2 and MAPKs has been determined by direct and indirect experiments (Müllberg et al. 1993, Schwarz et al. 2014, Fan and Derynck 1999; Gechtman et al. 1999; Díaz-Rodríguez et al. 2002; Fan, Turck, and Derynck 2003 & Xu and Derynck 2010). Specifically, the phosphorylation at residues Thr735 (Díaz-Rodríguez et al. 2002 & Xu and Derynck 2010) and Ser819 is required for ectodomains shedding. |
| (summation) | [Reaction:9662823] PLK2, MAPK14 phosphorylate ADAM17 [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The phosphorylation of disintegrin and metalloproteinase dom... (9663421)
