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Details on Person PKCs phosphorylate ADAM17

Class:Id	Reaction:9662840
_displayName	PKCs phosphorylate ADAM17
_doRelease	FALSE
_timestamp	2019-10-22 13:45:58
catalystActivity	[CatalystActivity:9662740] protein serine/threonine kinase activity of activated PKC alpha [plasma membrane]
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9662752] Murillo, Julieth, 2019-09-24
input	[Complex:9662793] ADAM17(215-827):Zn2+ [plasma membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9663428] The soluble interleukin-6 receptor is generated by shedding
modified	[InstanceEdit:9662900] Murillo, Julieth, 2019-09-24 [InstanceEdit:9663453] Murillo, Julieth, 2019-10-01 [InstanceEdit:9664303] Murillo, Julieth, 2019-10-22
name	PKCs phosphorylate ADAM17
output	[Complex:9662806] p-S,T-ADAM17(215-827):Zn2+ [plasma membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[BlackBoxEvent:9662818] iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane [Homo sapiens] [Reaction:9662773] ADAM17 binds Zn2+ [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9662890] R-HSA-9662840.1
summation	[Summation:9663446] Protein kinase Cs (PKCs) mediate the phosphorylation of disi...
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No pathways have been reviewed or authored by PKCs phosphorylate ADAM17 (9662840)