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Details on Person Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE

Class:IdLiteratureReference:9662830
_displayNameTumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE
_timestamp2019-09-24 10:08:32
author[Person:9662736] Adrain, Colin
[Person:9662847] Zettl, Markus
[Person:9662762] Christova, Yonka
[Person:9662750] Taylor, Neil
[Person:9662742] Freeman, Matthew
created[InstanceEdit:9662752] Murillo, Julieth, 2019-09-24
journalScience
modified[InstanceEdit:9662900] Murillo, Julieth, 2019-09-24
pages225-8
pubMedIdentifier22246777
titleTumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE
volume335
year2012
(literatureReference)[BlackBoxEvent:9662747] iRHOM2 transports ADAM17 from ER to the Golgi-network [Homo sapiens]
[Reaction:9662786] FURIN cleaves ADAM17 [Homo sapiens]
[BlackBoxEvent:9662818] iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane [Homo sapiens]
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No pathways have been reviewed or authored by Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE (9662830)